lunes, febrero 19, 2007

Time to use my summarising skills in school to good use eh?

What Should I Do With My Life? By Po Bronson, a guy who traveled for 2 years all over America and interviewed around 900 people. New York Bestseller List #1.

Summarised from 1 story in the book:

This guy Joe had a career in technical arbitrage (cashing in on inefficiencies of the market), one of the first guys to trade bonds versus bond futures. He'd figured he would retire by 35. But all he'd have then was money, he'd have nothing else.

So he enrolled in premed night classes at Hunter College and NYU, and eventually he gravitated to psychiatry. The book blahblahs, but eventually he found out that psychotic depression was still treated via electroshock.

The patient would be put under general anesthesia, then a current is then run through a patient's brain until it forces a seizure. This serves to trigger a 'cold reboot' of the brain, thereby releasing neurotransmitters in the brian, which control the release of cortisol(among other things definitely), of which psychotic depressives
has elevated levels of.

Patients need 6-10 of these treatments within 30 days.

Dissatisfied with this primitive form of treatment, this guy Joe hunted for a cure. Through research, he found that a compound called C-1073 has found to block both cortisol and progesterone.

Joe then wrote to the FDA and received approval for testing. Then Joe was faced with this dilemma; almost 20,000 psychotic depressives commit suicide each month. Should Joe license this to a major pharmaceutical company, or should they pursue it themselves, to ensure the fastest route to the market?

Thus Corcept Therapeutics was formed. Joe used his business skills to raise $26 million (I don't know how) thus using his skills to help what he believed in.

Quote from website:
"Our lead product, CORLUX, is currently in three Phase 3 clinical trials for the treatment of the psychotic features of psychotic major depression (PMD), a disorder that affects approximately three million adults in the United States each year and for which there are no FDA - approved treatments."

POINT OF STORY: Good use of former skill to help in present venture. Maybe you can use your skills to help what you want to do.

Maybe you can be a biotech executive? lol.